个人简介

现任西北老员工命科学学院经理、教授、副主任医师、博士生导师。担任英国威廉希尔唯一官网组织工程中心主任，国际组织工程学会会员，全国组织工程与再生医学专业委员会委员，陕西省细胞生物学会副理事长。《Tissue Engineering》、《Journal of Biomedical Material and related Research》两个刊物的审稿人。研究方向主要从事组织工程与再生医学的研究：（1）模式动物再生机制；（2）干细胞与再生医学；（3）生物材料与组织工程。

主要个人学习和工作经历：
2006.10-今 西北老员工命科学院 教授，博士生导师
2004.12-2006.10 秦都口腔英国威廉希尔公司颌面外科 副教授，副主任医师
2003.1-2004.12 新加坡国立大学工程学院，研究员
2002-2003 秦都口腔英国威廉希尔公司颌面外科 副教授，副主任医师
2000-2002 秦都口腔英国威廉希尔公司颌面外科 讲师，主治医师
1997-2000 秦都口腔英国威廉希尔公司颌面外科 博士
1994-1997 秦都口腔英国威廉希尔公司颌面外科 硕士
1988-1994 第四军医大学口腔医学系 大学

承担的科研项目

在研基金：

1．（2017）国家自然科学基金面上项目-前梯度蛋白与雪旺氏细胞在蝾螈肢体再生启动过程中的协同作用研究 课题负责人
2．（2016）陕西省科技统筹创新工程计划项目-油田原油污染土壤生态修复技术研究 课题负责人
3．（2014）横向项目-长庆特低渗透油藏微生物活化水改善水驱实验研究 课题负责人
4．（2013）科技部863项目子课题-中低温油藏微生物定向激活与模拟技术研究 课题负责人
5．（2013）国家自然科学基金面上项目-孤雌胚胎干细胞向软骨细胞定向诱导分化及构建组织工程软骨的研究 课题负责人
6．（2017）陕西省高等学校创新创业教育改革试点学院（系）建设项目

主要研究成果

Publications

1. Jie Tang, Yuan Yu, Hanxue Zheng, Lu Yin, Mei Sun, Wenjun Wang, Jihong Cui, Wenguang Liu, Xin Xie, Fulin Chen*. ITRAQ-based quantitative proteomic analysis of Cynops orientalis limb regeneration. BMC genomics. 2017,18(1):750.

2. Jihong Cui, Hanxue Zheng, Jing Zhang, Liyuan Jia, Yalong Feng, Wenjun Wang, Hongmin Li, Fulin Chen*. Profiling of glycan alterations in regrowing limb tissues of Cynops orientalis. Wound repair and regeneration. 2017,doi: 10.1111/wrr.12580.

3. Yang Rao, Jihong Cui, Lu Yin, Wei Liu, Wenguang Liu, Mei Sun, Xingrong Yan, Ling Wang, Fulin Chen*. Preclinical study of mouse pluripotent parthenogenetic embryonic stem cell derivatives for the construction of tissue-engineered skin equivalent. Stem Cell Research & Therapy. 2016,7(1):156.

4. Wei Liu, Lu Yin, Xingrong Yan, Jihong Cui, Wenguang Liu, Yang Rao, Mei Sun, Qi Wei, Fulin Chen*. Directing the Differentiation of Parthenogenetic Stem Cells Into Tenocytes for Tissue-Engineered Tendon Regeneration. Stem Cells Transl Med. 2016, pii: sctm.2015-0334.

5. Zhuoyue Chen, Jing Wei, Jun Zhu, Wei Liu, Jihong Cui, Hongmin Li, Fulin Chen*. Chm-1 gene-modified bone marrow mesenchymal stem cells maintain the chondrogenic phenotype of tissue-engineered cartilage. Stem Cell Research &Therapy. 2016,7(1):70.

6. Mei Sun, Man Jiang, Jihong Cui, Wei Liu, Lu Yin, Chunli Xu, Qi Wei, Xingrong Yan, Fulin Chen*. A novel approach for the cryodesiccated preservation of tissue-engineered skin substitutes with trehalose. Materials Science & Engineering C Materials for Biological Applications. 2015,60(2016):60-66.

7. Hongmin Li, Wei Zhou, Xingrong Yan, Jing Wei, Wenxin Geng, Jihong Cui, Xin Xie, Fulin Chen*. Osteoinductive nanohydroxyapatite bone substitute prepared via in situ hydrothermal transformation of cuttlefish bone. Journal of biomedical materials research Part B, Applied biomaterials. 2015,103(4):816-824.

8. Wei Liu, Xingyuan Yang, Xingrong Yan, Jihong Cui, Wenguang Liu, Mei Sun, Yang Rao, Fulin Chen*. Directing Parthenogenetic Stem Cells Differentiate into Adipocytes for Engineering Injectable Adipose Tissue. Stem Cells International. 2014,2014:423635.

9. Wenxin Geng, Dongyang Ma, Xingrong Yan, Liangqi Liu, Jihong Cui, Xin Xie, Hongmin Li, Fulin Chen*. Engineering tubular bone using mesenchymal stem cell sheets and coral particles. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2013,433(4):595-601.

10. Jie Zhao, Liangqi Liu, Jing Wei, Dongyang Ma, Wenxin Geng, Xingrong Yan, Jun Zhu, Huicong Du, Ying Liu, Liwen Li, Fulin Chen*. A Novel Strategy to Engineer Small-Diameter Vascular Grafts From Marrow-Derived Mesenchymal Stem Cells. Artificial Organs. 2012,36(1):93-101.

11. Ying Liu, Zhilong Jia, Liwen Li, Fulin Chen*. A genetically synthetic protein-based cationic polymer for siRNA delivery. Medical Hypotheses. 2011,76(2):239-240.

12. Liangqi Liu, Wei Wu, Xiaoye Tuo, Wenxin Geng, Jie Zhao, Jing Wei, Xingrong Yan, Wei Yang, Liwen Li*, Fulin Chen*. Novel Strategy to Engineer Trachea Cartilage Graft With Marrow Mesenchymal Stem Cell Macroaggregate and Hydrolyzable Scaffold. Artificial Organs. 2010,34(5):426-433.

13. Wei Zhou, Chun Han, Yingliang Song, Xingrong Yan, Dehua Li, Zhiguo Chai, Zhihong Feng, Yan Dong, Liwen Li, Xin Xie, Fulin Chen*, Yimin Zhao*. The performance of bone marrow mesenchymal stem cell - Implant complexes prepared by cell sheet engineering techniques. Biomaterials. 2010,31(12):3212-3221.

获得的教学和科研表彰

获奖情况：
1．陕西省科学技术一等奖：低渗透油田本源微生物采油技术研究与应用 第一完成人
2．陕西省高等学校科学技术一等奖：低渗透油田本源微生物采油技术研究与应用 第一完成人
3．培养骨髓基质干细胞成骨能力的实验研究-获中华医学会西安分会青年优秀论文一等奖
4．Restoration of tissue engineered bone graft loading a titanium dental implant- Traveling Award of Chinese Division of IADR
5．The paper, “The effect of rhBMP-2 on canine osteoblasts seeded onto 3D bioactive
polycaprolactone scaffolds”, was awarded Best Paper in the 3rd Biomedical Engineering Society (Singapore) Symposium held on 21 May 2004, Ngee Ann Polytechnic.
6．羟基磷灰石－碳酸钙双相陶瓷人工骨（西安市科技进步二等奖）